New discoveries in the field of metabolism by applying single-cell and spatial omics.

"Declaration of competing interest The authors declare that there are no conflicts of interest."

"This work was supported by the National Key Research and Development Program of China (Program No.: 2019YFA0904300), Shenzhen Science and Technology Program (Program No.: JCYJ20220530150404009), and the Guangdong Basic and Applied Basic Research Foundation (Grant No.: 2022A1515110608). Baocai Xie: Investigation, Writing - Original draft preparation, Reviewing and Editing, Visualization, Funding acquisition; Dengfeng Gao: Writing - Original draft preparation, Data curation; Biqiang Zhou: Data curation, Visualization; Shi Chen: Supervision, Writing - Reviewing and Editing, Funding acquisition; Lianrong Wang: Supervision, Writing - Reviewing and Editing, Funding acquisition."