Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α-Synuclein at Physiological pH with Sodium Salts.

"The authors declare the following competing financial interest(s): Robert I. Horne is a consultant of WaveBreak Therapeutics (formerly Wren Therapeutics). Michael A. Metrick has been a consultant of WaveBreak Therapeutics. Sean Chia has been an employee of WaveBreak Therapeutics. Georg Meisl is an employee of WaveBreak Therapeutics. Michele Vendruscolo is a founder of WaveBreak Therapeutics."

"M.A.M. II would like to acknowledge the NIH/Cambridge scholars program and the Cambridge Trust for financial support. We would also like to thank ARCHER, MARCOPOLO, and CIRCE high performance computing resources for the computer time. Z.F.B. would like to acknowledge the Federation of European Biochemical Societies (FEBS) for financial support (LTF). We are furthermore grateful for financial support from the Cambridge Centre for Misfolding Diseases. This work was supported by the UKRI (10059436, 10061100). Parts of the figures were created with BioRender.com."