Effect of a music intervention on anxiety in adult critically ill patients: a multicenter randomized clinical trial.

"Declarations Ethics approval and consent to participateThis study will be conducted according to the principles of the Declaration of Helsinki (64th WMA General Assembly, Fortaleza, Brazil, October 2013) and in accordance with the Medical Research Involving Human Subjects Act. The study protocol has received ethical approval from the Medical Ethical Review Committee of the Erasmus Medical Center in Rotterdam prior to the beginning of the study. Eligible patients and/or their legal representative received an information folder and an informed consent form, and had a maximum of 48 h to consider their participation. Participation in this study was on voluntary basis. Consent for publicationYes. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This research was partly funded by the Music as Medicine foundation, Erasmus MC, Rotterdam, The Netherlands, Grant number: N/A."

"Trial registration Netherlands Trial Register: NL8595, Registered, 1 April 2020. ClinicalTrials.gov ID: NCT04796389, Registered retrospectively, 12 March 2021"