Tailored psychological intervention for anxiety or depression in COPD (TANDEM): a randomised controlled trial.

"Conflict of interest: L. Steed reports support for the present manuscript from the NIHR Health Technology Assessment programme (project number 13/146/02), and also reports lecture honoraria from the IPCRG, outside the submitted work. K. Marshall reports support for the present manuscript from the NIHR Health Technology Assessment programme (project number 13/146/02), and also reports lecture honoraria, outside the submitted work. S.J. Singh reports support for the present manuscript from the NIHR Health Technology Assessment programme (project number 13/146/02); in addition, S.J. Singh also reports grants from the NIHR (NIHR 202020 and senior investigator grant), Wellcome Doctoral Training Programme, HTA Project Grant (NIHR 131015), NIHR DHSC/UKRI COVID-19 Rapid Response Initiative, NIHR Global Research Group (NIHR 17/63/20) and Actegy Limited, lecture honoraria from GSK, Ministry of Justice, CIPLA and Sherbourne Gibbs, advisory board participation with NICE (Expert Adviser Panel – Long COVID) and the Wales Long COVID Advisory Board (expired), and leadership roles with the ATS (Pulmonary Rehabilitation Assembly Chair), RCP Pulmonary Rehabilitation Accreditation Scheme and NACAP Audit for Pulmonary Rehabilitation, outside the submitted work. M. Underwood is chief investigator or co-investigator on previous and current research grants from the UK NIHR, Arthritis Research UK and on grants funded by the Australian NHMRC and Norwegian MRC; he was an NIHR Senior Investigator until March 2021. He has received travel expenses for speaking at conferences from the professional organisations hosting the conferences. He is a director and shareholder of Clinvivo Ltd. He is part of an academic partnership with Serco Ltd, funded by the European Social Fund. He is a co-investigator studies that are, or have had, additional support from Stryker Ltd. Until March 2020 he received a fee as an NIHR journal editor and editors group member. V. Wileman reports support for the present manuscript from the NIHR Applied Research Collaboration (ARC) North Thames. P. White is a chief investigator or co-investigator on multiple previous and current research grants from the NIHR, and reports travel expenses for speaking at conferences from the professional organisations hosting the conferences. H. Pinnock reports support for the present manuscript from the NIHR Health Technology Assessment programme (project number 13/146/02), and also reports lecture honoraria from Sandoz, Teva and Boehringer Ingelheim, outside the submitted work. S.J.C. Taylor, R. Sohanpal, S. Priebe, A. Healey, S. Waseem, M.J. Kelly and C.M. Roberts report support for the present manuscript from the NIHR Health Technology Assessment programme (project number 13/146/02). All other authors have nothing to disclose."

"Support statement: This study is independent research, funded by the NIHR Health Technology Assessment programme (project number 13/146/02). S.J.C. Taylor and V. Wileman were supported by the NIHR Applied Research Collaboration (ARC) North Thames. P. Font-Gilabert and A. Healey were supported by the NIHR ARC South London at King's College Hospital NHS Foundation Trust. S.J. Singh is supported by the NIHR Leicester Biomedical Research Centre. M. Underwood is supported by University Hospitals Coventry and Warwickshire. The views expressed in this publication are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. Funding information for this article has been deposited with the Crossref Funder Registry."

"The TANDEM trial reports no benefit from a cognitive behavioural approach intervention focused particularly on breathlessness in people with advanced COPD and anxiety/depression. More research is needed for these patients with high levels of unmet need. https://bit.ly/3QDCB8v"