Cell-free DNA 5-hydroxymethylcytosine is highly sensitive for MRD assessment in acute myeloid leukemia.

Authors:
Shao J; Shah S; Ganguly S; Zu Y; He C and 1 more

Journal:
Clin Epigenetics

Publication Year: 2023

DOI:
10.1186/s13148-023-01547-0

PMCID:
PMC10464230

PMID:
37620919

Journal Information

Full Title: Clin Epigenetics

Abbreviation: Clin Epigenetics

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics, Medical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"availability of data and materials the raw 5hmc sequencing data are available in the national center for biotechnology information gene expression omnibus database . availability of data and materials the raw 5hmc"

Code Sharing
Evidence found in paper:

"Declarations Ethics approval and consent to participateThis study was approved by the institutional review board at Houston Methodist Hospital. The informed consent was waived. Competing interestsC.H. is an inventor of the 5hmC-Seal method. All other authors declare no competing interests related to the work described. Competing interests C.H. is an inventor of the 5hmC-Seal method. All other authors declare no competing interests related to the work described."

Evidence found in paper:

"Funding This work was supported by an American Cancer Society Research Scholar Grant RSG-17-044-01-LIB (Z.L.). C.H. is a Howard Hughes Medical Institute Investigator."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025