An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis.

"study supervision: p a m and b j data availability all data supporting the findings of this study are available within the paper supplementary information and general repository figshare 10 6084/m9 figshare 23549964 10 6084/m9 figshare 23550108 10 6084/m9 figshare 23550117 10 6084/m9 figshare 23550129). data availability--figshare"

"Competing interests The authors declare no competing interests."

"We thank the donors at the Beijing chest hospital who consented to this study and provided the blood samples. The gamma-irradiated Mtb strains, Mtb antigenic fractions and proteins mentioned in the methods section were obtained from BEI resources, NIAID, NIH. This work was funded in part by the Bill and Melinda Gates Foundation, Grant No: R-571-000-030-720 to P.A.M., National Natural Sciences Foundation Grant (81661128044) to B.J. and by the Bill & Melinda Gates Foundation (INV-038660) to B.J. and P.A.M. B.J. is a Wellcome Trust Investigator (207487/C/17/Z)."