Activation of transient receptor potential vanilloid 1 ameliorates tau accumulation-induced synaptic damage and cognitive dysfunction via autophagy enhancement.

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"CONFLICT OF INTEREST STATEMENT The authors declare no competing interests."

"The authors thank Prof. Jian‐Zhi Wang (Tongji Medical College, Huazhong University of Science and Technology) for kindly providing the 293‐hTau cell line. We appreciate Dr. Weiwei Gao (Institute of Neuroscience, Fujian Medical University) and Mr. Pin Zou (School of Basic Medical Sciences, Fujian Medical University) for the use of the vibratome. We also acknowledge the Public Technology Service Center of Fujian Medical University for offering technical assistance with confocal microscopy analysis. The research was supported by the National Natural Science Foundation of China (82001128, 82271449, and 81970993), the Natural Science Foundation of Fujian Province (2021J01672), and the start‐up funding of Fujian Medical University (XRCZX2019039). The funding sources are not involved in study design, data collection and interpretation, and drafting of the manuscript."