Fathers' preconception smoking and offspring DNA methylation.

"availability of data and materials summary statistics for the epigenome-wide association analyses reported in the manuscript are available from https://doi"

"Declarations Ethics approval and consent to participateEthical permissions were obtained for each study wave from the local ethics committee in each of the participating centres. The ethical approval reference numbers are listed on www.rhinessa.net. All study participants provided written informed consent prior to participation. Permission to extract information about themselves and family members from national registers were obtained from each participant in the Northern European study centres. For children and adolescents participating in the additional study groups presented in the Additional file 1, Supplementary methods and data written informed consents were given by the parents/guardian, as required by the local ethics committees. Competing interestsThe authors have no competing interests to declare. Competing interests The authors have no competing interests to declare."

"Funding Coordination of the RHINESSA study has received funding from the Research Council of Norway (Grants Nos. 274767, 214123, 228174, 230827 and 273838), ERC StG project BRuSH #804199, the European Union's Horizon 2020 research and innovation programme under grant agreement No. 633212 (the ALEC Study), the Bergen Medical Research Foundation and the Western Norwegian Regional Health Authorities (Grants Nos. 912011, 911892 and 911631). Study centres have further received local funding from the following: Bergen: the above grants for study establishment and coordination, and, in addition, World University Network (REF and Sustainability grants), Norwegian Labour Inspection and the Norwegian Asthma and Allergy Association. Albacete and Huelva: Sociedad Española de Patología Respiratoria (SEPAR) Fondo de Investigación Sanitaria (FIS PS09). Gøteborg, Umeå and Uppsala: the Swedish Heart and Lung Foundation, the Swedish Asthma and Allergy Association. Reykjavik: Iceland University. Melbourne: National Health and Medical Research Council (NHMRC) of Australia (research grants 299901 and 1021275). Tartu: the Estonian Research Council (Grant No. PUT562). Århus: The Danish Wood Foundation (Grant No. 444508795), the Danish Working Environment Authority (Grant No. 20150067134), Aarhus University (PhD scholarship). ALSPAC funding: EPIC arrays age 15–17, John Templeton Foundation (60828) and EPIC arrays age 24, MRC (MC_UU_12013/2) & CLOSER (MRC and ESRC)."