Discovery of new Schistosoma mansoni aspartyl protease inhibitors by structure-based virtual screening.

Journal Information

Full Title: Mem Inst Oswaldo Cruz

Abbreviation: Mem Inst Oswaldo Cruz

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Tropical Medicine

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"then a medicinal chemistry inspection filter based on using tanimoto coefficient and maccs keys was employed to ensure the structural novelty of virtual hits in relation to known anti-schistosomal compounds available on chembl database (id: chembl612893)."

Code Sharing
Evidence found in paper:

"All authors contributed to editing and writing the final version of the manuscript: The authors report no conflicts of interest"

Funding Disclosure
Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025