Hyperferritinemic sepsis, macrophage activation syndrome, and mortality in a pediatric research network: a causal inference analysis.

"Declarations Ethics approval and consent to participateThe study was approved by the Institutional Review Board at University of Utah Central IRB #70976. Consent for publicationNot applicable. Competing interestsThe authors had no competing interest but they did have the following. Authors Carcillo, Berg, Wessel, Pollack, Meert, Hall, Newth, Doctor, Shanley, Cornell, Harrison, Zuppa, and Dean received support for article research from the NICHD. Dr. Carcillo and Dr Park’s institutions also received funding from the National Institute of General Medical Sciences. Dr. Pollack disclosed that his research is supported by philanthropy from Mallinckrodt Pharmaceuticals. Dr. Hall received funding from LaJolla Pharmaceuticals (service as a consultant), unrelated to the current submission. Dr. Newth received funding from Philips Research North America. Dr. Doctor’s institution received funding from the Department of Defense and Kalocyte. Dr. Shanley received funding from Springer publishing, International Pediatric Research Foundation, and Pediatric Academic Societies. Dr. Cornell disclosed he is co-founder of Pre-Dixon Bio. The remaining authors have disclosed that they do not have any potential conflicts of interest. Competing interests The authors had no competing interest but they did have the following. Authors Carcillo, Berg, Wessel, Pollack, Meert, Hall, Newth, Doctor, Shanley, Cornell, Harrison, Zuppa, and Dean received support for article research from the NICHD. Dr. Carcillo and Dr Park’s institutions also received funding from the National Institute of General Medical Sciences. Dr. Pollack disclosed that his research is supported by philanthropy from Mallinckrodt Pharmaceuticals. Dr. Hall received funding from LaJolla Pharmaceuticals (service as a consultant), unrelated to the current submission. Dr. Newth received funding from Philips Research North America. Dr. Doctor’s institution received funding from the Department of Defense and Kalocyte. Dr. Shanley received funding from Springer publishing, International Pediatric Research Foundation, and Pediatric Academic Societies. Dr. Cornell disclosed he is co-founder of Pre-Dixon Bio. The remaining authors have disclosed that they do not have any potential conflicts of interest."

"Funding Supported, in part, by grant R01GM108618 (to Dr. Carcillo and Dr Park) and 1K23GM148827-01 (to Dr Kernan) from the National Institute of General Medical Sciences, and by 5U01HD049934-10S1 (to Dr Carcillo), from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services and the following cooperative agreements: U10HD049983, U10HD050096, U10HD049981, U10HD063108, U10HD63106, U10HD063114, U10HD050012, and U01HD049934."