Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.

"the three top-performing methods from the disease module identification dream challenge were compiled in the monet toolbox and released to the public for use ( https://github com/bergmannlab/monet git ) ( ).; the algorithm used for batch correction is fully documented and available as an r function which can be downloaded from https://github com/edammer/tampor ."

"Declaration of Competing Interest: A.I.L, N.T.S., and D.M.D. are co-founders of Emtherapro Inc. The authors declare no conflicts of interest."

"Funding This study was supported by the following National Institutes of Health funding mechanisms: NIA AG063755, NIA AG068024, R01AG061800, and U01AG061357 (N.T.S). ROSMAP is supported by NIA grants P30AG10161, P30AG72975, R01AG15819, R01AG17917, U01AG46152, and U01AG61356 (D.A.B.). ROSMAP resources can be requested at https://www.radc.rush.edu. D.F. is supported by the Krembil Foundation, the Koerner New Scientist Award, the Canadian Institutes of Health Research, the CAMH Foundation, and the Canadian Foundation for Innovation. E.ST. is supported by the Ontario Graduate Scholarship."