The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer.

Authors:
Wang J; He T; Gao Q; Chang H; Dai X and 5 more

Journal:
Genes Dis

Publication Year: 2023

DOI:
10.1016/j.gendis.2023.03.026

PMCID:
PMC10491908

PMID:
37692497

Journal Information

Full Title: Genes Dis

Abbreviation: Genes Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics & Heredity

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"Conflict of interests The authors have declared no conflict of interests."

Evidence found in paper:

"Funding This work was supported by grants from 10.13039/100014717National Nature Science Foundation of China (No. 81973356, 81902826 and 82273963), 10.13039/501100006606Natural Science Foundation of Tianjin (No. 21JCZDJC00060 and 21JCYBJC00180), the Fundamental Research Funds for the Central Universities of Nankai University (No. ZB22010404, 3206054, 91923101, 63213082, and 92122017)."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025