Similar but distinct: The impact of biomechanical forces and culture age on the production, cargo loading, and biological efficacy of human megakaryocytic extracellular vesicles for applications in cell and gene therapies.

Publication Year: 2023

DOI:
10.1002/btm2.10563

PMCID:
PMC10486331

PMID:
37693047

Journal Information

Full Title: Bioeng Transl Med

Abbreviation: Bioeng Transl Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Engineering, Biomedical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
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Core Indicators
Evidence found in paper:

"data s1: supporting information."

Code Sharing
Evidence found in paper:

"CONFLICT OF INTEREST STATEMENT Eleftherios Terry Papoutsakis is a paid consultant for STRM.BIO, which aims to use MkEVs for cell and gene therapy applications. Eleftherios Terry Papoutsakis is the co‐inventor on several active or pending patents encompassing MkEVs and their miRNA cargo. Will Thompson reports no conflicts of interest."

Evidence found in paper:

"FUNDING INFORMATION This work was supported by the US National Science Foundation (grant number CBET‐1804741) and the Department of Education GAANN Fellowship (grant number P200A210065)."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025