Development and characterization of a recombinant silk network for 3D culture of immortalized and fresh tumor-derived breast cancer cells.

Publication Year: 2023

DOI:
10.1002/btm2.10537

PMCID:
PMC10487315

PMID:
37693069

Journal Information

Full Title: Bioeng Transl Med

Abbreviation: Bioeng Transl Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Engineering, Biomedical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
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Core Indicators
Data Sharing
Evidence found in paper:

"the code used to create the volcano plots is available on github ( https://github com/kblust/vulcanoplot_breastcancer2dvs3d ) 3 3 1 figure 1a describes the various steps required to form the fn-silk networks with breast cancer cells."

Evidence found in paper:

"CONFLICT OF INTEREST STATEMENT My Hedhammar has shares in Spiber Technologies AB, a company that aims to commercialize recombinant spider silk."

Evidence found in paper:

"We thank the Bioinformatics and Expression Analysis (BEA) core facility at the Karolinska Institute in Huddinge for performing the RNA‐seq experiment and initial data analysis. We thank Professor Johan Hartman and Dr. Xinsong Chen for kindly donating the SK‐BR‐3, MCF‐7, and MDA‐MB‐231 and for providing the patient biopsies. We thank Cellaria for generously providing us with the Wood and PB cells as well as the Renaissance Essential Tumor Medium. We are grateful to Lars Hiertas Minne for supporting this work and Spiber Technologies AB for providing recombinant spider silk proteins."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025