Virological evidence of the impact of non-pharmaceutical interventions against COVID-19 in Ecuador, a resource-limited setting.

"Disclosure statement We have no conflicts of interest to disclose."

"We thank Arne Kühne for technical support. We thank Carlo Fischer for the critical reading of the manuscript. All patient data were managed in anonymized databases by the INSPI. Clinical symptoms were retrieved from medical charts. The study was approved by the Ecuadorian Ministry of Health (MSP-MSP-2021-0006-O-FDQ) and the Ethics committee of the Espiritu Santo University in Guayaquil, Ecuador (2022-002A). Conceptualization (AM-S, JCZ, JFD), data curation (AB, DdM, MP, JG,JG, BW, A-LS, MO, MJB, MG, AO, SS), formal analysis (AM-S, AB, DdM, MP, JG, BW, A-LS, MO, MJB, MG, AO, SS, JCZ, JFD), funding acquisition (JFD), investigation (AM-S, AB, DdM, MP, JG, BW, A-LS, MO, MJB, MG, AO, SS, JCZ, JFD), methodology (AM-S, AB, DdM, MP, JG, BW, A-LS, MO, MJB, MG, AO, SS, JCZ, JFD), project administration (AM-S, AO, JCZ, JFD), resources (AM-S, AB, DdM, MP, JG, BW, A-LS, MO, MJB, MG, AO, SS, JCZ, JFD), software (AM-S, A-LS, BW), visualization (AM-S, BW, A-LS), writing–original draft (AM-S, AB, DdM, MP, JG, BW, A-LS, MO, MJB, MG, AO, SS, JCZ, JFD), and writing–review & editing (AM-S, JFD)."