Is later-life depression a risk factor for Alzheimer's disease or a prodromal symptom: a study using post-mortem human brain tissue?

"Declarations Ethics approval and consent to participateEthical approval for this work was provided by the Greater Manchester East NRES committee (ref 17/NW/0126). All tissue collected by both the South West Dementia Brain Bank and the Douglas Bell Canada Brain Bank is donated with consent from the individual’s next of kin. Consent is given at the time of donation for the tissue to be used in research studies which have obtained ethical approval. Consent for publicationNot applicable. Competing interestsThis work was funded by BRACE Alzheimer’s Research and the David Telling Charitable Trust.  The South West Dementia Brain Bank is funded by BRACE, the Alzheimer’s Society & Alzheimer’s Research UK as part of Brains for Dementia Research.  The Douglas Bell Brain Bank is funded by the fonds du recherche du Quebec-Santé through the Réseau québécois sur le suicide, les troubles de l’humeur et les troubles associés, as well as Brain Canada Foundation.Sinclair has received funding from the Alzheimer’s Society (grant 518), the Elizabeth-Blackwell institute for Health Research University of Bristol and the Wellcome Trust Institutional Strategic Support Fund (204813/Z/16/Z), BRACE, the David Telling Charitable Trust and a travel grant from the Gatsby Foundation/Royal College of Psychiatrists. Love is in receipt of funding from the Medical Research Council (MR/W004984/1, MR/T018569/1), UK Dementia Research Institute, and Alzheimer's Brain Bank UK. Morisaki is funded by the Alzheimer’s Society (grant 518). GT, SC, ME, AM and AB-C have no conflicts of interest to disclose. Competing interests This work was funded by BRACE Alzheimer’s Research and the David Telling Charitable Trust.  The South West Dementia Brain Bank is funded by BRACE, the Alzheimer’s Society & Alzheimer’s Research UK as part of Brains for Dementia Research.  The Douglas Bell Brain Bank is funded by the fonds du recherche du Quebec-Santé through the Réseau québécois sur le suicide, les troubles de l’humeur et les troubles associés, as well as Brain Canada Foundation. Sinclair has received funding from the Alzheimer’s Society (grant 518), the Elizabeth-Blackwell institute for Health Research University of Bristol and the Wellcome Trust Institutional Strategic Support Fund (204813/Z/16/Z), BRACE, the David Telling Charitable Trust and a travel grant from the Gatsby Foundation/Royal College of Psychiatrists. Love is in receipt of funding from the Medical Research Council (MR/W004984/1, MR/T018569/1), UK Dementia Research Institute, and Alzheimer's Brain Bank UK. Morisaki is funded by the Alzheimer’s Society (grant 518). GT, SC, ME, AM and AB-C have no conflicts of interest to disclose."

"Funding This work was funded by BRACE Alzheimer’s Research and the David Telling Charitable Trust. The South West Dementia Brain Bank is funded by BRACE, the Alzheimer’s Society & Alzheimer’s Research UK as part of Brains for Dementia Research. The Douglas Bell Brain Bank is funded by the fonds du recherche du Quebec-Santé through the Réseau québécois sur le suicide, les troubles de l’humeur et les troubles associés, as well as Brain Canada Foundation."