Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease.

"data availability the datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request. competing interests a patent (application # 18/334212"

"Competing interests A patent (application # 18/334,212) was applied by Scottish Rite for Children. H.K.W.K. and C.M. were listed as inventors. The status of the patent is pending. The patent covered the method of the BMP2 hydrogel preparation and its application in osteonecrosis treatment. Other authors declare no financial or non-financial competing interests."

"This study was funded by NIAMS R01AR078311. The funder played no role in study design, data collection, analysis and interpretation of data, or the writing of this manuscript. The authors would like to thank Amanda McLerran for technical assistance in animal work, Reuel Cornelia and Richard Banlaygas for their histologic work, Ila Oxendine for morphometric analyses."