Noradrenaline transporter PET reflects neurotoxin-induced noradrenaline level decrease in the rat hippocampus.

"Declarations Ethics approval and Consent to participateThe protocols for the present animal experiments were approved by the Animal Ethics Committee of the National Center for Gelotology and Geriatrics. The study was carried out in compliance with the ARRIVE guidelines. All applicable international, national and institutional guidelines for the care and use of animals were followed. This article does not describe any studies with human participants. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was supported by Research Funding for Longevity Sciences (21–10) from National Center for Geriatrics and Gerontology, Obu, Japan."