Poor Subjective Sleep Quality Predicts Symptoms in Irritable Bowel Syndrome Using the Experience Sampling Method.

"CONFLICTS OF INTEREST Guarantor of the article: Qasim Aziz, PhD, FRCP. Specific author contributions: R.T., L.V., L.V.O., D.K., and Q.A.: planned the study. R.T. and S.P.: conducted the study and collected the data. R.T., J.C., J.E., H.V., H.F., and M.V.D.H.: interpreted the data. R.T.: drafted the manuscript. All authors edited the draft manuscript to arrive at the final version. Financial support: Funding for the development and validation of the ESM tool was provided by Grunenthal GmbH, Aachen, Germany to Maastricht University. Potential competing interests: D.K. has received research funding from Grunenthal, Allergan, Will Pharma, Rome Foundation, ZonMw, MLDS, UEG, Horizon 2020, Horizon Europe, and speaker's fee from Dr Falk (paid to host institution). R.T., L.V., H.F., S.P., J.C., J.E., L.V.O., M.V.D.H., and Q.A. have no conflicts of interest. Study HighlightsWHAT IS KNOWN✓ Sleep disturbances are more common in patients with irritable bowel syndrome compared with those in healthy subjects.✓ Sleep quality is an independent factor affecting gastrointestinal (GI) symptoms.WHAT IS NEW HERE✓ Poor subjective sleep quality predicts next-day abdominal pain and lower-GI symptom scores.✓ Worse abdominal pain and lower-GI symptom scores do not predict subjective sleep quality the following night.✓ Objective sleep measures are not associated with next-day GI symptoms."

"Financial support: Funding for the development and validation of the ESM tool was provided by Grunenthal GmbH, Aachen, Germany to Maastricht University."