A Proofreading Mutation with an Allosteric Effect Allows a Cluster of SARS-CoV-2 Viruses to Rapidly Evolve.

"supplementary table s2 supplementary material online. having detected an initial temporal signal in all data"

"We thank the researchers who have shared genome data through the Global Initiative on Sharing All Influenza Data (GISAID). A.H.M. was supported by a studentship through the UKRI as part of the Artificial Intelligence, Machine Learning and Advanced Computing Centre for Doctoral Training (AIMLAC CDT) (grant code EP/S023992/1, project reference 2414958). Computational resources were provided by Advanced Research Computing at Cardiff (ARCCA) and Medical Research Council Cloud Infrastructure for Microbial Bioinformatics (MRC CLIMB) (grant code MR/T030062/1). We further acknowledge resources provided through COVID-19 Genomics UK Consortium (COG-UK), which is supported by funding from the Medical Research Council (MRC) part of UKRI (grant code: MC_PC_19027). For the purpose of open access, the author has applied a CC BY public copyright license (where permitted by UKRI, “Open Government Licence” or “CC BY-ND public copyright licence” may be stated instead) to any author accepted manuscript version arising. We extend our appreciation to Dr Zack Saud and Professor Richard Stanton for their initial guidance and resources for experimental work."