Elucidating disease-associated mechanisms triggered by pollutants via the epigenetic landscape using large-scale ChIP-Seq data.

"sample codes and all raw results of the tf enrichment analyses (i e deg-motifea dar-motifea deg-chipea and dar-chipea) were deposited at https://github com/zouzhaonan/dar_moa/ ."

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. The funders had no role in the design of the study, the collection, analysis, and interpretation of data, or in writing the manuscript. Competing interests The authors declare that they have no competing interests. The funders had no role in the design of the study, the collection, analysis, and interpretation of data, or in writing the manuscript."

"Funding This work was supported by Grants-in-Aid for Scientific Research (KAKENHI), Japan Society for the Promotion of Science [22J15229 to ZZ, 23KF0048 to ZZ and SO, 22H02819, 23H04954 to SO]; Japan Science and Technology Agency [SPRING JPMJSP2110 to ZZ, PRESTO JPMJPR1942, NBDC JPMJND2202, and ERATO JPMJER2101 to SO]; Japan Agency for Medical Research and Development [PRIME JP22gm6710001, BINDS JP22ama121017 to SO], and Kyoto University [MIP and KMS-FUND to ZZ]. Funding for open access charge: Japan Science and Technology Agency [JPMJND2202]."