Clinical Characterization of [¹⁸F]T-008, a Cholesterol 24-Hydroxylase PET Ligand: Dosimetry, Kinetic Modeling, Variability, and Soticlestat Occupancy.

"DISCLOSURE This study was funded by Takeda Pharmaceutical Co. Ltd. Terry Brown, Shining Wang, Wei Yin, and Johannes Tauscher are employees of Takeda Pharmaceutical Co. Ltd. and own stock or stock options. Cristian C. Constantinescu is an employee of Invicro, which was contracted by Takeda Pharmaceutical Co. Ltd. to conduct the study. Olivier Barret and Danna Jennings are former employees of Invicro. Under the direction of the authors and funded by Takeda Pharmaceutical Co. Ltd., Aimee Jones and Erin Aldera of Oxford PharmaGenesis, Oxford, U.K., provided medical writing support for this publication. Editorial assistance in formatting, proofreading, copyediting, and fact-checking was also provided by Oxford PharmaGenesis. No other potential conflict of interest relevant to this article was reported."

"This study was funded by Takeda Pharmaceutical Co. Ltd. Terry Brown, Shining Wang, Wei Yin, and Johannes Tauscher are employees of Takeda Pharmaceutical Co. Ltd. and own stock or stock options. Cristian C. Constantinescu is an employee of Invicro, which was contracted by Takeda Pharmaceutical Co. Ltd. to conduct the study. Olivier Barret and Danna Jennings are former employees of Invicro. Under the direction of the authors and funded by Takeda Pharmaceutical Co. Ltd., Aimee Jones and Erin Aldera of Oxford PharmaGenesis, Oxford, U.K., provided medical writing support for this publication. Editorial assistance in formatting, proofreading, copyediting, and fact-checking was also provided by Oxford PharmaGenesis. No other potential conflict of interest relevant to this article was reported."