Phase I clinical evaluation of <sup>99m</sup>Tc-labeled Affibody molecule for imaging HER2 expression in breast cancer.

Publication Year: 2023

DOI:
10.7150/thno.86770

PMCID:
PMC10526658

PMID:
37771776

Journal Information

Full Title: Theranostics

Abbreviation: Theranostics

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Diagnostic Imaging

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"Competing Interests: Maryam Oroujeni, Annika Loftenius, Fredrik Y. Frejd are employees of Affibody AB. Anna Orlova and Vladimir Tolmachev are members of Technical advisory board of Affibody AB."

Evidence found in paper:

"This research was financially supported by the Swedish Cancer Society (CAN 21 1485 Pj) and the Ministry of Science and Higher Education of the Russian Federation (075-15-2019-1925)."

Evidence found in paper:

"This was a prospective, open-label, nonrandomized phase I diagnostic study in patients with untreated primary breast cancer (ClinicalTrials.gov Identifier: NCT05203497). The study protocol was approved by the Scientific Council of Cancer Research Institute and Board of Medical Ethics, Tomsk National Research Medical Center of the Russian Academy of Sciences (protocol №13, 09.11.2021), and all patients signed a written informed consent form."

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Last Updated: Aug 05, 2025