A genome-wide CRISPR/Cas9 screen identifies DNA-PK as a sensitiser to <sup>177</sup>Lutetium-DOTA-octreotate radionuclide therapy.

Publication Year: 2023

DOI:
10.7150/thno.84628

PMCID:
PMC10526672

PMID:
37771787

Journal Information

Full Title: Theranostics

Abbreviation: Theranostics

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Diagnostic Imaging

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"Competing Interests: The authors have declared that no competing interest exists with respect to the current research. Outside this study RJH declares being shareholder in Telix Pharmaceuticals."

Evidence found in paper:

"The Molecular Genomics Core, the Advanced Centre for Cancer Cell Isolation and Flow Cytometry and the Centre for Advanced Histology and Microscopy (CAHM) at Peter MacCallum Cancer Centre. This research was supported by the Australian Cancer Research Foundation for the Molecular Genomics Core, the Advanced Centre for Cancer Cell Isolation and Flow Cytometry and the Centre for Advanced Histology and Microscopy (CAHM) at Peter MacCallum Cancer Centre. This work was supported by an Accelerator Award generously provided by the Neuroendocrine Tumor Research Foundation (NETRF)."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025