Early detection of autism using digital behavioral phenotyping.

"code availability custom code used in this study is available at: https://github com/samperochon/perochon_et_al_nature_medicine_2023 ."

"Competing interests K.C., S.E., G.D. and G.S. developed technology related to the app that has been licensed to Apple, Inc. and both they and Duke University have benefited financially. K.C., G.D. and G.S. have a patent (11158403B1) related to digital phenotyping methods. G.D. has invention disclosures and patent apps registered at the Duke Office of License and Ventures. G.D. reports being on the Scientific Advisory Boards of Janssen Research & Development, Akili Interactive, Labcorp, Roche, Zyberna Pharmaceuticals, Nonverbal Learning Disability Project and Tris Pharma, Inc., and is a consultant for Apple, Inc., Gerson Lehrman Group and Guidepoint Global, LLC. G.D. reports grant funding from NICHD, NIMH and the Simons Foundation; receiving speaker fees from WebMD and book royalties from Guilford Press, Oxford University Press and Springer Nature Press. G.S. reports grant funding from NICHD, NIMH, Simons Foundation, NSF, ONR, NGA and ARO and resources from Cisco, Google and Amazon. G.S. was a consultant for Apple, Inc., Volvo, Restore3D and SIS when this work started. G.S. is a scientific advisor to Tanku and has invention disclosures and patent apps registered at the Duke Office of Licensing and Ventures. G.S. received speaker fees from Janssen when this work started. G.S. is currently affiliated with Apple, Inc.; this work, paper drafting and core analysis were started and performed before the start of such affiliation and are independent of it. The remaining authors declare no competing interests. All authors received grant funding from the NICHD Autism Centers of Excellence Research Program."

"This project was funded by a Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Autism Center of Excellence Award P50HD093074 (to G.D.), National Institute of Mental Health (NIMH) R01MH121329 (to G.D.), NIMH R01MH120093 (to G.S. and G.D.) and the Simons Foundation (G.S. and G.D.). Resources were provided by National Science Foundation (NSF), Office of Naval Research (ONR), National Geospatial-Intelligence Agency (NGA), Army Research Office (ARO), and gifts were given by Cisco, Google and Amazon. We wish to thank the many caregivers and children for their participation in the study, without whom this research would not have been possible. We gratefully acknowledge the collaboration of the physicians and nurses in Duke Children’s Primary Care and members of the NIH Duke Autism Center of Excellence research team, including several clinical research coordinators and specialists. We thank E. Sturdivant from Duke University for proofreading the paper."