Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.

"data availability cryo-em maps have been deposited in the electron microscopy data bank (emdb) with the accession numbers emd-18269 (tg2541) and emd-18268 (ps19).; corresponding refined atomic models have been deposited in the protein data bank (pdb) under accession numbers pdb:8q96 (tg2541) and pdb:8q92 (ps19). data availability cryo-em maps have been deposited in the electron microscopy data bank (emdb) with the accession numbers emd-18269"

"Declarations Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was funded by the Medical Research Council, as part of UK Research and Innovation (MC-UP-A025-1013 to SHWS and MC-U105184291 to MG). It was also supported by Eli Lilly and Company (to MG) and the Rainwater Charitable Foundation (to MG)."