Different Frameworks, Similar Results? Head-to-Head Comparison of the Generic Preference-Based Health-Outcome Measures CS-Base and EQ-5D-5L.

"Declarations FundingFinancial support for this study was provided by the PhD grant sponsored by the Chinese Scholarship Council and the University Medical Center Groningen. The following author is employed by the sponsors: Xin Zhang. The funding agreement ensured the independence of the authors in designing the study, interpreting the data, and writing and publishing the manuscript. Conflicts of InterestXin Zhang, Karin M. Vermeulen, and Paul F.M. Krabbe have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. As an extension of the CS-Base ePROM, MAPR framework, and the DD method presented in this paper, additional PROMs and software are developed by Paul F.M. Krabbe as part of academic/commercial activities. Commercial activities are part of the spin-off company Château Santé that is affiliated with the University of Groningen. Ethics ApprovalThis study was exempt from review by the Medical Ethics Review Committee at the University Medical Center of Groningen. It issues waivers stating that the pertinent Dutch Legislation (the Medical Research Involving Human Subjects Act) does not apply to survey research where participants fill out a single questionnaire, which does not pose additional risks. A third-party vendor, Dynata, collected data of this study from Dynata’s panel of patients in the USA. Dynata complies with the ethical guidelines and standards set forth in the Market Research Society Code of Conduct. Consent to ParticipateAll participants provided informed consent through completion and return of the survey of the study. The purpose of the study was explained prior to data collection. Consent for PublicationAll participants consented to have their data included in publications when registering with the research market company (Dynata). Availability of Data and MaterialThe datasets generated during the current study are not publicly available because of the storage on the dedicated Château-Santé server but are available from the corresponding author on reasonable request. Code AvailabilityThe code is available upon reasonable request from the corresponding author. Authors’ ContributionsXZ contributed to the data analysis and interpretation, figures preparation, and writing and reviewing the article. KMV helped with the data interpretation, and contributed to the manuscript writing and language phrasing and improvement. PFMK contributed to the study concept and design, as well as to the interpretation of the data, writing, and the critical reviewing of the article in terms of important intellectual content. He also approved the version to be published. Conflicts of Interest Xin Zhang, Karin M. Vermeulen, and Paul F.M. Krabbe have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. As an extension of the CS-Base ePROM, MAPR framework, and the DD method presented in this paper, additional PROMs and software are developed by Paul F.M. Krabbe as part of academic/commercial activities. Commercial activities are part of the spin-off company Château Santé that is affiliated with the University of Groningen."

"Funding Financial support for this study was provided by the PhD grant sponsored by the Chinese Scholarship Council and the University Medical Center Groningen. The following author is employed by the sponsors: Xin Zhang. The funding agreement ensured the independence of the authors in designing the study, interpreting the data, and writing and publishing the manuscript."