Retinal mid-peripheral capillary free zones are enlarged in cognitively unimpaired older adults at high risk for Alzheimer's disease.

"Declarations Ethics approval and consent to participateThe study adhered to the tenets of the Declaration of Helsinki, and informed consent from all subjects was obtained prior to experimental data collection after an explanation of the nature and possible consequences of the study. The study was part of the Atlas of Retinal Imaging in Alzheimer’s Study (ARIAS; PJS served as principal investigator for ARIAS) which took place at the University of Rhode Island and Butler Hospital Memory and Aging Program, Providence, RI, between 2020 and 2022 and was approved by the BayCare Institutional Review Board (IRB). Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This study is part of the Atlas of Retinal Imaging in Alzheimer’s Study (ARIAS) supported by a generous grant from the Morton Plant Mease Health Care Foundation (Clearwater, FL, USA) to PJS and SS (co-PIs) and NIH/NIA R21AG079794 to EA. JAP was supported by the National Heart Lung and Blood Institute under grant no. K23HL150217-04. JA was supported by NIH/NIA R01AG079241, R21AG074153, and the Warren Alpert Foundation. PJS served as the principal investigator for ARIAS."