Dexmedetomidine alleviates cognitive impairment by promoting hippocampal neurogenesis via BDNF/TrkB/CREB signaling pathway in hypoxic-ischemic neonatal rats.

Authors:
Chen X; Chen A; Wei J; Huang Y; Deng J and 9 more

Journal:
CNS Neurosci Ther

Publication Year: 2023

DOI:
10.1111/cns.14486

PMCID:
PMC10805444

PMID:
37830170

Journal Information

Full Title: CNS Neurosci Ther

Abbreviation: CNS Neurosci Ther

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Therapeutics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"full unedited gel/blot from this study can be found in data s1 2 8 we utilized the markers c3 and s100a10 to identify a1 and a2 phenotype astrocytes respectively."

Code Sharing
Evidence found in paper:

"CONFLICT OF INTEREST STATEMENT The authors declare no competing interests."

Evidence found in paper:

"FUNDING INFORMATION This research was funded by the National Natural Science Foundation of China (grant nos. 82001166 and 82171186); and the Natural Science Foundation of Fujian Province (grant nos. 2021J01366 and 2021J01385); the Training Project for Talents of Fujian Provincial Health Commission (grant nos. 2020GGA013 and 2022GGA007)."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025