Genomic Heterogeneity of Cryptosporidium parvum Isolates From Children in Bangladesh: Implications for Parasite Biology and Human Infection.

Authors:
Carey M; Arju T; Cotton JA; Alam M; Kabir M and 4 more

Journal:
J Infect Dis

Publication Year: 2023

DOI:
10.1093/infdis/jiad257

PMCID:
PMC10629705

PMID:
37832036

Journal Information

Full Title: J Infect Dis

Abbreviation: J Infect Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Communicable Diseases

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
6/6
100.0% Transparent
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Core Indicators
Evidence found in paper:

"the sequences of the bangladesh isolates were obtained as previously described for c hominis [ ] and are deposited in the ncbi's sequence read archive bioproject prjeb14327 (sra; supplementary table 1 )."

Evidence found in paper:

"for consistency in analysis all genome sequences were analyzed in parallel and aligned to the cryptosporidium parvum iowa ii reference genome sequence (cryptodb version 53; [ ]); the analytic code and additional detail are provided at https://github com/maureencarey/cparvum_genomes_manuscript ."

Evidence found in paper:

"Potential conflict of interests. W. A. P. is a consultant for TechLab, a company that makes diagnostic tests for cryptosporidiosis. All other authors report no potential conflicts. Potential conflict of interests."

Evidence found in paper:

"Financial support. This work was supported by the National Institute of Allergy and Infectious Diseases (grant numbers R21 AI-109118 to C. A. G., and R01 AI-043596 to C. A. G. and W. A. P.); the Bill and Melinda Gates Foundation (grant number OPP1100514 to A. S. G. F.); University of Virginia Engineering-in-Medicine seed grant to M. A. C. and W. A. P.; the Henske Family Foundation; and the Wellcome Trust (grant number 206194). M. A. C. was supported by the PhRMA Foundation Postdoctoral Fellowship in Translational Medicine and Therapeutics and the University of Virginia Trans-University Microbiome Initiative. TechLab, Inc donated the Giardia / Cryptosporidium QUIK CHEKS used in the parent study. Work at icddr, b was supported by the core donors (Government of the People’s Republic of Bangladesh, Global Affairs Canada, the Swedish International Development Cooperation Agency, and UKAid). Financial support."

Evidence found in paper:

"Clinical Trials Registration . NCT02764918."

Open Access
Paper is freely available to read
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Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025