Between but Not Within-Species Variation in the Distribution of Fitness Effects.

"all scripts required for the processing of data and the polydfe input files used in this analysis are available at ( https://github com/j-e-james/treedfescripts ).; we calculated aic weights and generated bootstrap datasets using the r functions provided in polydfe ( ) available at https://github com/paula-tataru/polydfe . data availability the genetic data underlying this article are available as vcf files at: https://entrepot recherche data gouv fr/dataset xhtml? persistentid=doi"

"site-based annotation (4-fold degenerate and 0-fold degenerate sites) of detected snps was generated using the python script newannotateref py available at https://github com/fabbyrob/science/blob/master/pileup_analyzers/newannotateref py ( ).; full documentation of bioinformatics pipelines used to generate these vcf files is available at https://github com/gentree-h2020-eu/gentree .; the custom scripts used to calculate all summary statistics are available at: https://github com/j-e-james/treedfescripts .; all scripts required for the processing of data and the polydfe input files used in this analysis are available at ( https://github com/j-e-james/treedfescripts ).; we calculated aic weights and generated bootstrap datasets using the r functions provided in polydfe ( ) available at https://github com/paula-tataru/polydfe .; all other scripts used to conduct these analyses are available at https://github com/j-e-james/treedfescripts .; all statistical analyses and plotting were conducted in r using scripts available at https://github com/j-e-james/treedfescripts .; full documentation of bioinformatics pipelines used to generate the vcf files including snp filtering steps are available at https://github com/gentree-h2020-eu/gentree .; code for all other analysis and bioinformatic steps is available at https://github com/j-e-james/treedfescripts ."

"Conflict of interest statement. None declared."

"J.J. was supported by a grant from the Wenner-Gren Foundation. The present project was supported by the European Union's Horizon 2020 Research and Innovation Programme grant agreement no. 676876 (Gentree). S.C.G.-M. was supported by the French government in the framework of the IdEX Bordeaux University “Investments for the Future” programme/GPR Bordeaux Plant Sciences. The computations were enabled by resources in project SNIC 2022/22-910 provided by the Swedish National Infrastructure for Computing (SNIC) at UPPMAX, partially funded by the Swedish Research Council (VR) through grant agreement no. 2018-05973. We are grateful to Sylvain Glémin for his input on an earlier draft of this manuscript, and to two anonymous reviewers for their valuable insights into this work."