In situ fNIRS measurements during cognitive behavioral emotion regulation training in rumination-focused therapy: A randomized-controlled trial.

"appendix a supplementary data the following are the supplementary data to this article: supplementary data 1 data availability data will be made available on request."

"Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"Funding This work was supported by the fortune funding program at the University of Tuebingen [grant number F1331582]. We further acknowledge support from the Open Access Publication Fund of the University of Tuebingen."

"We recruited participants via emails and flyers at the University Hospital of Tuebingen, the University of Tuebingen and via outpatient psychotherapists. All procedures are in line with the Declaration of Helsinki in its latest version and were approved by the ethics committee at the University Hospital and University of Tuebingen. The study protocol is registered at ClinicalTrials.gov (NCT04560192). All participants gave their written informed consent prior to data collection. Participants could be included in the study if they were between 18 and 60 years old, had never participated in a study with a Trier Social Stress Test (TSST) procedure and did not meet any of the following exclusion criteria: diabetes mellitus, kidney insufficiency, hypertension, dysrhythmia, cushing syndrome, current substance abuse, adrenal insufficiency, cortisone medication, pacemaker, craniocerebral trauma as well as any current primary mental or personality disorder, except ICD-10 diagnosis F32.x, F33.x and F34.1 in the group of the depressive sample (MDD). For this latter group, acute suicidality, extraordinarily severe depressive symptoms (BDI-II > 50) and strong decompensation under social stress in the past also led to exclusion. In the group of healthy controls (HC), only participants with low trait rumination (RRS score ≤ 2) and without any primary mental or personality disorder (current as well as in the past) were included."