Inhibition of DNA-dependent protein kinase catalytic subunit boosts rAAV transduction of polarized human airway epithelium.

Authors:
Ning K; Zhang X; Feng Z; Hao S; Kuz CA and 6 more

Journal:
Mol Ther Methods Clin Dev

Publication Year: 2023

DOI:
10.1016/j.omtm.2023.101115

PMCID:
PMC10568418

PMID:
37841417

Journal Information

Full Title: Mol Ther Methods Clin Dev

Abbreviation: Mol Ther Methods Clin Dev

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Medicine, Research & Experimental

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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"Declaration of interests Z.Y. and J.F.E. are paid consultants for Spirovant Sciences, Inc."

Evidence found in paper:

"The study was supported by 10.13039/100000002NIH grants AI150877 and AI156448. We are grateful to the Confocal Microscopy Core Laboratory of The 10.13039/100006727University of Kansas Medical Center. The STED confocal microscope was supported by an 10.13039/100000002NIH grant S10 OD 023625. We thank the Cells and Tissue Core of Center for Gene Therapy, the University of Iowa (NIH grant DK054759) for providing the primary HAE-ALI cultures. The funder had no role in study design, data collection and interpretation, or the decision to submit the work for publication."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025