The differences in drug disposition gene induction by rifampicin and rifabutin are unlikely due to different effects on important pregnane X receptor (NR1I2) splice variants.

Journal Information

Full Title: Naunyn Schmiedebergs Arch Pharmacol

Abbreviation: Naunyn Schmiedebergs Arch Pharmacol

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"Declarations Ethical approvalEthics approval was obtained from the responsible Ethics Committee of the Medical Faculty of Heidelberg University (ethical approval number S-649/2012). Consent to participateAll patients gave their written informed consent before being enrolled in the study. Consent for publicationAll authors read and approved the manuscript for submission. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

Evidence found in paper:

"Funding Open Access funding enabled and organized by Projekt DEAL. Julie Nilles receives an allowance from Boehringer Ingelheim Pharma GmbH & Co. KG."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025