ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer.

"Declarations Ethics approval and consent to participateAll the research programs have been approved by the Animal Experiment Committee, an animal protection and ethics institution of Fujian Maternal and Child Health Hospital. Each participant signed informed consent before participating in this study. Consent for publicationNot applicable. Competing interestsThe authors declare no potential conflicts of interest. Competing interests The authors declare no potential conflicts of interest."

"Funding This work was supported by the Fund of National Key R&D Program of China (Grant no. 2022YFC2704303); National Nature Science Foundation of China (Grant no. 82203739); the Fujian Health Young and Middle-aged Scientific Research Major Project (grant no. 2021ZQNZD011); the Startup Fund for scientific research, Fujian Medical University (Grant no.2020QH2041); the Natural Science Foundation of Fujian Province (Grant no. 2020J02059 and 2021J01404), and Joint Funds for the Innovation of Science and Technology, Fujian Province (Grant no. 2020Y9160 and 2021Y9157)."