Combined Reactive and Volitional Step Training Improves Balance Recovery and Stepping Reaction Time in People With Parkinson's Disease: A Randomised Controlled Trial.

"The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article."

"Funding: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by a Parkinson’s NSW seed grant. Dr Paulo H. S. Pelicioni was a recipient of a Coordenação de Aperfiçoamento de Pessoal de Nivel Superior PhD scholarship (Grant number: BEX 2194/15-5). Prof Stephen R. Lord is supported by NHMRC Investigator Grant."

"We conducted an assessor-blinded, randomized, controlled trial involving 44 people with PD who were randomly allocated into intervention or control groups. A sample size calculation for a Poison regression analysis was conducted with the following assumptions: a 70% fall rate in the control group, a 10% dropout rate, a significance level of <.05 and a power of 0.8. This revealed that 44 eligible participants were required (22 in each group) to detect a 50% reduction in the number of laboratory-induced falls in the intervention group. Participants were enrolled between September 2018 and September 2019. We prospectively registered the trial protocol on the Australian New Zealand Clinical Trials Registry (ACTRN12618001515280). The University New South Wales Human Research Ethics Committee approved the study protocol, and written informed consent was obtained from all participants before their participation."