Community health workers in clinical research at the example of a phase IIIb/ IV antimalarial drug trial conducted in five African countries.

"Declarations of competing interest IBF and SD are full-time employees at Medicines for Malaria Venture, JS is a full-time employee at Shin-Poong Pharmaceutical and SAB is a consultant paid by Shin-Poong Pharmaceutical. The other authors declare no conflict of interest."

"Funding This work was supported by Medicines for Malaria Venture (MMV), Geneva, Switzerland. A full list of donors to MMV is available on its website [www.mmv.org] and in its annual report. MMV contributed to the writing of the manuscript and the decision to submit the paper for publication as detailed in the contribution section of this manuscript. The Bill & Melinda Gates Foundation contributed to the cost of open-access publication: This work was supported, in part, by the Bill & Melinda Gates Foundation [INV-007155 /19-BMGF-006]. Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission."