Effect of antiplatelet and anticoagulant medication use on injury severity and mortality in patients with traumatic brain injury treated in the intensive care unit.

"Declarations Ethics approvalThe ethics committee of Helsinki University Hospital (194/13/03/14 §97), the Finnish National Institute for Health and Welfare (THL/713/5.05.01/2014 and THL/1298/5.05.00/2019), Statistics Finland (TK-53–1047-14), the Social Insurance Institution of Finland (Kela 23/522/2018), the Office of the Data Protection Ombudsman (Dnro 2713/402/2016 28.10.16), and all the participating university hospitals’ research committees approved this study. Consent to participateAll ethics/research committees waived the need for informed patient consent given the retrospective nature of the study and all the procedures being performed were part of the routine care. Consent for publicationNot applicable as all committees waived the need for informed patient consent. Conflict of interestM. S. has received a travel grant and lecture fee from BARD Medical (Ireland). J. R. has received a lecture fee from Bayer (Finland). These activities have no relation to any of the work presented in this article. Authors J. V. and J. S. have had personal grants from Maire Taponen Foundation. R. R. has had personal grants from Finska Läkaresällskapet, Medicinska Understödsföreningen Liv & Hälsa, Svenska Kulturfonden. Authors J. J. V., M. R., S. B., T. A-K., S. H., and R. L. have no competing financial interests to report. Conflict of interest M. S. has received a travel grant and lecture fee from BARD Medical (Ireland). J. R. has received a lecture fee from Bayer (Finland). These activities have no relation to any of the work presented in this article. Authors J. V. and J. S. have had personal grants from Maire Taponen Foundation. R. R. has had personal grants from Finska Läkaresällskapet, Medicinska Understödsföreningen Liv & Hälsa, Svenska Kulturfonden. Authors J. J. V., M. R., S. B., T. A-K., S. H., and R. L. have no competing financial interests to report."

"Funding Open Access funding provided by University of Helsinki (including Helsinki University Central Hospital). Independent funding support has been received from Helsinki University Hospital (State funding, Finland VTR TYH2018227, and VTR TYH2023330); Finska Läkaresällskapet; Medicinska Understödsföreningen Liv & Hälsa; Svenska Kulturfonden; Maire Taponen Foundation. The funders had no role in the study design, data collection, data analysis, data interpretation, or writing of the manuscript. The first and last authors had full access to all the data in the study and had final responsibility for the decision to submit for publication."