Cerebrospinal fluid pleocytosis is associated with HIV-1 neuroinvasion during acute infection.

"Conflicts of interest There are no conflicts of interest."

"We thank the RV254/SEARCH 010 participants, the International NeuroHIV Cure Consortium that is funded by the National Institute of Mental Health, and staff from the Thai Red Cross AIDS Research Centre, Institute of HIV Research and Innovation (IHRI), Chulalongkorn University, and Armed Forces Research Institute of Medical Sciences for their valuable contributions to this study. We are grateful to the Thai Government Pharmaceutical Organization, ViiV Healthcare, Gilead Sciences, and Merck for providing the antiretroviral medications for this cohort. Financial support: the RV254/SEARCH 010 study is supported by cooperative agreements (WW81XWH18–2–0040) between the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., and the US Department of Defense (DOD) and by an intramural grant from the Thai Red Cross AIDS Research Centre. This research was funded, in part, by the US NIAID (AAI20052001), The National Institute of Mental Health (NIMH) (R01MH106466), National Institute of Neurological Disorders and Stroke (NINDS) (R01NS084911), and NIMH support of the International NeuroHIV Cure Consortium. Antiretroviral therapy for RV254/SEARCH 010 participants was supported by the Thai Government Pharmaceutical Organization, Gilead Sciences, Merck, and ViiV Healthcare."