Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuation.

Journal Information

Full Title: Leukemia

Abbreviation: Leukemia

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Hematology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
5/6
83.3% Transparent
Transparency Indicators
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Core Indicators
Evidence found in paper:

"data availability the raw scrna+tcr??-seq data generated in this study are available in the european genome-phenome archive under accession code egas00001005044. the processed scrna+tcr??-seq data and the seurat-objects are available at zenodo under 10 5281/zenodo 7330586.; the processed tcr?-seq data including the pr1-classifier for tcrgp are available at zenodo under 10 5281/zenodo 7330586. supplementary figures and supplementary data legends supplementary data 1 supplementary data 2 supplementary data 3 supplementary data 4 publisher's note springer nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. data availability the raw scrna+tcr??-seq data generated in this study are available in the european genome-phenome archive under accession code egas00001005044"

Evidence found in paper:

"code availability the code to reproduce the key findings is available at https://github com/janihuuh/cml_stop_manu ."

Evidence found in paper:

"Competing interests P.D. is currently employed by Nygen Analytics AB. M.I. is currently employed by Bristol Myers Squibb. U.O.S. has received honoraria from Incyte. H.H.H. has received honoraria from Novartis, Bristol Myers Squibb, and Incyte. A.B. has received honoraria from Novartis and MSD. G.K. is currently employed by Nygen Analytics AB. A.K. is currently employed by Bristol Myers Squibb. S.M. has received honoraria from Bristol Myers Squibb and DrenBio and research funding from BMS, Novartis, and Pfizer. All other authors declare no conflicts of interests."

Evidence found in paper:

"Funding Open Access funding provided by University of Helsinki (including Helsinki University Central Hospital)."

Protocol Registration
Open Access
Paper is freely available to read
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Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025