High BMI and the risk for incident type 1 Diabetes Mellitus: a systematic review and meta-analysis of aggregated cohort studies.

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding None."

"For this systematic review and meta-analysis, we searched the published literature using the Ovid MEDLINE & EMBASE databases (from inception to June 13, 2022). The search structures, Medical Subject Headings (MeSH), and keywords were tailored to each database by a medical research librarian with experience in systematic reviews. The terms “type 1”, “early onset”, “juvenile”, and “insulin dependent”, were used to identify type 1 diabetes. The complete MEDLINE and EMBASE search strings are listed in Additional file : Table S1. The search was not limited by language or publication date. Abstracts of the articles identified by the search were read and evaluated on the basis of the inclusion criteria. Reference lists of the included articles were searched manually. A list of the included articles was sent to experts in the field for their review. Our findings are reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines []. The study protocol is registered in PROSPERO (CRD42023417321)."