High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages.

"Declarations Ethics approval and consent to participateThe protocols and the use of animals were approved by and in accordance with the University of Louisville Animal Care and Use Committee. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"Funding This work was partly supported by NIH (ES023693, ES028911, and HL147856), KSEF-148-RED-502–16-381, and Kentucky Lung Cancer Research Program to Dr. Qunwei Zhang. This work was also partly supported by P30ES030283 from the National Institute for Environmental Health Sciences."