Identification of potential immunologic resilience in the healing process of diabetic foot ulcers.

Publication Year: 2023

DOI:
10.1111/iwj.14465

PMCID:
PMC10898407

PMID:
37926487

Journal Information

Full Title: Int Wound J

Abbreviation: Int Wound J

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Traumatology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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"our research not only holds the promise of unveiling the pathogenesis of dfu but may also offer new targets for the prevention and treatment of dfu 2 2 1 we collected gene expression data from dfu patients from the publicly available gene expression omnibus (geo) database gse134431 includes gene expression files of nine ulcer samples from healer four ulcer samples from no-healer and eight healthy skin samples from dfu by high-throughput sequencing gse143735 includes gene expression files of five skin samples from healer four skin samples from no-healer and four healthy skin samples from dfu by high-throughput sequencing gse165816 includes single-cell rna sequencing (scrnaseq) of skin samples from seven dfu with no-healer 12 skin samples from dfu with healer and 10 healthy skin samples2 2 we processed the data using the limma package in r which included background correction normalization and the calculation of gene expression values."

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"CONFLICT OF INTEREST STATEMENT The authors declare no potential conflicts of interest."

Evidence found in paper:

"FUNDING INFORMATION This work was supported by the Open Project of the State Key Laboratory on the Causes and Prevention of High Incidence in Central Asia Jointly Constructed by the Ministry and the Province (SKL‐HIDCA‐2019‐19)."

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Last Updated: Aug 05, 2025