Automated analysis of gray matter damage in aged mice reveals impaired remyelination in the cuprizone model.

Publication Year: 2023

DOI:
10.1111/bpa.13218

PMCID:
PMC10901622

PMID:
37927164

Journal Information

Full Title: Brain Pathol

Abbreviation: Brain Pathol

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pathology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
5/6
83.3% Transparent
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Evidence found in paper:

"for cell segmentation the training dataset has been made available under "mollenkamp thiemo 2023 'replication data for: gray matter damage - training dataset for cell segmentation of dab mouse brain images' https://doi org/10 7910/dvn/jgeqps harvard dataverse v1".; this set was used in conjunction with the publicly available tnbc dataset ( https://doi org/10 5281/zenodo 1175282 ) and the monuseq data segmentation challenge: this data can be found under creative commons license cc by-nc-sa 4 0. data availability statement the algorithms used for cell detection as well as cell and pixel classification along with example images for comprehension of the workflow are publicly available at https://github com/thiemommoellenkamp/gray-matter-damage-in-aged-mice git ."

Evidence found in paper:

"data availability statement the algorithms used for cell detection as well as cell and pixel classification along with example images for comprehension of the workflow are publicly available at https://github com/thiemommoellenkamp/gray-matter-damage-in-aged-mice git ."

Evidence found in paper:

"CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest."

Evidence found in paper:

"FUNDING INFORMATION This research received no external funding."

Protocol Registration
Open Access
Paper is freely available to read
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Replication
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Tool: rtransparent

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Last Updated: Aug 05, 2025