Efficacy of intracytoplasmic sperm injection in women with non-male factor infertility: A systematic review and meta-analysis.

"Youth Fund of the 1st Hospital of Lanzhou University; Natural Science Foundation of Gansu Province 10.13039/501100004775"

"This systematic review was conducted according to the Cochrane Handbook for systematic reviews of interventions and has been registered in PROSPERO with the number CRD42023427004 on May 16, 2023. We also followed the preferred reporting items for systematic reviews and meta‐analyses (PRIMSA) checklist to report this study (Table ). Material and methods: We searched Medline, Embase, and the Cochrane Central Register of Controlled Trials from inception to March 2023. Randomized controlled trials (RCTs) comparing the efficacy between ICSI and IVF in patients with non‐male factor infertility were included. The main outcomes were the live birth rate (LBR), fertilization rate (FR), and total fertilization failure (TFF). The pooled estimates were calculated using the random‐effects models as relative risk (RR) with 95% confidence intervals (CIs). This systematic review and meta‐analysis was registered in PROSPERO (CRD42023427004)."