Construction of miRNA-mRNA regulatory network indicates potential biomarkers for primary open-angle glaucoma.

"the datasets generated and/or analysed during the current study are available in the gene expression omnibus public database gse138125 (mrna-seq) gse231760 (mirna-seq) gse27276 (genome-wide expression in tm) and gse105269 (mirna-seq in ah) ( https://www ncbi nlm nih gov/ )."

"Declarations Ethics approval and consent to participateAll experiments associated with human participants in this study complies with the ethical standards of the Second Xiangya Hospital research committee and the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants enrolled in the study. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This work was supported by the National Natural Science Foundation of China [grant numbers 81970801]; the Hunan Province research and development plan funding projects in key areas [grant numbers 2020SK2133]; the Natural Science Foundation of Hunan Province, China [grant numbers 2023JJ40004, 2023JJ40003, 2023JJ70014, 2019JJ40001]; and the Science and Technology Foundation of Aier Eye Hospital Group, China [grant numbers AR2206D4, AR2206D2, AR2206D5]."