Developing a digital informed consent app: opportunities and challenges of a new format to inform and obtain consent in public health research.

"Declarations Ethics approval and consent to participateThis study was carried out in preparation for the start of the Sarphati Cohort. All procedures were approved by the Registration Committee of the City of Amsterdam. Exemption from the Medical Research Involving Human Subjects Act (WMO) was granted by the Medical Ethical Committee of Amsterdam UMC, location AMC (W16_340 # 16.398). In addition, the Sarphati Cohort received legal approval from the Amsterdam Personal Data Commission (CPA). CPA is a committee that advises on the privacy policy of the Amsterdam municipality and its implementation. Only after a positive assessment of the Extensive Risk Analysis on Information Security and Privacy and the Privacy Impact Analysis of the data-infrastructure and the app, could the development on the app be started in the second quarter of 2017. All the methods were carried out in accordance with relevant national and international guidelines and regulations as laid down in the Declaration of Helsinki. Participation for the test was on voluntary basis. Prior to the test participants signed an informed consent for conducting and audiotaping the interviews. As an incentive participants received a gift voucher of 10 euros. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This study was carried out in preparation for the start of the Sarphati Cohort and was funded by the City of Amsterdam."

"Declarations: Ethics approval and consent to participateThis study was carried out in preparation for the start of the Sarphati Cohort. All procedures were approved by the Registration Committee of the City of Amsterdam. Exemption from the Medical Research Involving Human Subjects Act (WMO) was granted by the Medical Ethical Committee of Amsterdam UMC, location AMC (W16_340 # 16.398). In addition, the Sarphati Cohort received legal approval from the Amsterdam Personal Data Commission (CPA). CPA is a committee that advises on the privacy policy of the Amsterdam municipality and its implementation. Only after a positive assessment of the Extensive Risk Analysis on Information Security and Privacy and the Privacy Impact Analysis of the data-infrastructure and the app, could the development on the app be started in the second quarter of 2017. All the methods were carried out in accordance with relevant national and international guidelines and regulations as laid down in the Declaration of Helsinki. Participation for the test was on voluntary basis. Prior to the test participants signed an informed consent for conducting and audiotaping the interviews. As an incentive participants received a gift voucher of 10 euros.: Consent for publicationNot applicable.: Competing interestsThe authors declare no competing interests. Ethics approval and consent to participate: This study was carried out in preparation for the start of the Sarphati Cohort. All procedures were approved by the Registration Committee of the City of Amsterdam. Exemption from the Medical Research Involving Human Subjects Act (WMO) was granted by the Medical Ethical Committee of Amsterdam UMC, location AMC (W16_340 # 16.398). In addition, the Sarphati Cohort received legal approval from the Amsterdam Personal Data Commission (CPA). CPA is a committee that advises on the privacy policy of the Amsterdam municipality and its implementation. Only after a positive assessment of the Extensive Risk Analysis on Information Security and Privacy and the Privacy Impact Analysis of the data-infrastructure and the app, could the development on the app be started in the second quarter of 2017. All the methods were carried out in accordance with relevant national and international guidelines and regulations as laid down in the Declaration of Helsinki. Participation for the test was on voluntary basis. Prior to the test participants signed an informed consent for conducting and audiotaping the interviews. As an incentive participants received a gift voucher of 10 euros."