Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system.

"Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"Funding This work was supported by a DOD Kidney Cancer Research Program Translational Research Partnership Award (KC180135 to SA and SST), a Mary Gates Research Scholarship to MF, and philanthropic gifts in support of kidney cancer research to the Warren Lab at FHCC. This research was also supported by the Cellular Imaging, Flow Cytometry, Specimen Processing and Research Cell Bank, and Genomics and Bioinformatics Shared Resources of the Fred Hutch/University of Washington Cancer Consortium (P30 CA015704-40), and the Scientific Computing Infrastructure at FHCC funded by NIH/ORIP grant S10OD028685."