BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia.

"data availability rnaseq data are deposited at geo (gse 242432) and available from the corresponding author on reasonable request ( https://www ncbi nlm nih gov/geo/query/acc cgi? data availability rnaseq data are deposited at geo (gse 242432"

"Competing interests The authors declare no competing interests."

"Funding This work was generated within the European Reference Network for Paediatric Cancer (PAEDCAN). It was supported by grants from the German Research Foundation (FOR2036, ER599/3-2 to ME; CRC1160, 256073931-Z02 to MB; CRC/TRR167, 259373024-Z01 to MB; CRC1453, 431984000-S1 to MB, CRC1479, 441891347- S1 to MB), the European Research Council (ERC Starting Grant no. 638145 “ApoptoMDS” to ME), the German Federal Ministry of Education and Research (BMBF) (“MyPred” to ME, CF and CMN; no 01GM1911A; MIRACUM-FKZ 01ZZ1801B to MB and EkoEstMed–FKZ 01ZZ2015 to GA) and the DKTK (to CF). YW was supported by the CSC scholarship, JR by the Spemann Graduate School of Biology and Medicine, University of Freiburg. ME was funded by the Berta-Ottenstein-Program for Advanced Clinician Scientists, Faculty of Medicine, University of Freiburg. The authors acknowledge the contribution of the Center of Inborn and Acquired Blood Diseases at the Freiburg Center for Rare Diseases, Freiburg, Germany. Open Access funding enabled and organized by Projekt DEAL."