Downregulation of pro-surfactant protein B contributes to the recurrence of early-stage non-small cell lung cancer by activating PGK1-mediated Akt signaling.

"Declarations Ethics approval and consent to participateAll animal experiments were performed in accordance with the ethical policies and procedures approved by the Laboratory Animal Welfare and Ethics Committee of the Army Medical University (Approval no. AMUWEC20223173). Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This study was partially supported by the National Natural Science Foundation of China (81672283, to H.J.), the Chongqing Natural Science Foundation (cstc2021jcyj-msxmX0350, to H.J.), Key Project of Sichuan Provincial Department of Science and Technology (23SYSX0073, to B.H.) and the Beijing Natural Science Foundation (7232168, to R.-T.W.)."